The effect of high intensity interval training on gene expression of inflammatory biomarkers in fast- and slow muscles of rats
| Autor: | Bahman Hasanvand, Rahman Soori, Mahsa Rastegar MM, Sadegh Abbasian |
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| Jazyk: | perština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Armaghane Danesh Bimonthly Journal, Vol 21, Iss 12, Pp 1164-1178 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1728-6514 1728-6506 |
| Popis: | Background and aims: Lipocalin-2 (LCN-2) with Interleukin1-β (IL1-β) are inflammatory proteins that induced the inflammatory reactions due to insufficient of physical activity. The purpose of the current study was to determine the effect of high intensity interval training on Lipocalin-2 and Interleukin1-β gene expressions in fast- and slow muscles of rats. Methods: In the current study 20 Wistar rats were divided into HIIT and control groups. HIIT protocol was performed 60 min in each session for four sessions in each week. After warm-up, HIIT group was carried out 15 × 4 min bouts of HIIT with 85 to 90% of VO2max that continued with three min recovery (between each bout of HIIT) with 70% of VO2max. LCN-2 and IL1-β and their gene translations were evaluated by commercial kits and Real-Time PCR method, respectively. Results: Findings shown that VO2max was significantly increased and serum levels of LCN-2 and IL1-β were significantly decreased (p |
| Databáze: | Directory of Open Access Journals |
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