Determination of acetylsalicylic acid in tablets with salicylate ion selective electrode in a Batch Injection Analysis system

Autor: Fernandes Julio Cesar B., Garcia Carlos Alexandre B., Grandin Luciane A., Oliveira Neto Graciliano de, Godinho Oswaldo E.S.
Jazyk: angličtina
Rok vydání: 1998
Předmět:
Zdroj: Journal of the Brazilian Chemical Society, Vol 9, Iss 3, Pp 249-251 (1998)
Druh dokumentu: article
ISSN: 0103-5053
Popis: The feasibility of the use of a Batch Injection Analysis (BIA) system for potentiometric determination of acetylsalicylic acid in tablets, with a membrane ion selective electrode, was investigated. There is no significant difference between the results obtained by the proposed method and those obtained by the Standard British Pharmacopaeia method12 at the 95% confidence level. Values of 4% and 2.5% for R.S.D. were obtained by the application of the BIA-potentiometric method and for the injections respectively. About 90 determinations per hour can be performed with the proposed BIA potentiometric method.
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