Chronic gastritis may predict risk of cerebral small vessel disease

Autor: Cunsheng Wei, Chang Tan, Xuemei Zhang, Xin Shen, Zongliang Xu, Junrong Li, Gelin Xu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Gastroenterology, Vol 23, Iss 1, Pp 1-6 (2023)
Druh dokumentu: article
ISSN: 1471-230X
DOI: 10.1186/s12876-023-03009-6
Popis: Abstract Background and purpose Chronic gastritis, especially that caused by helicobacter pylori (HP) infection, has been associated with increased risk of ischemic stroke. But the relationship between chronic gastritis and cerebral small vessel disease (CSVD) remains largely undetermined. This study aimed to determine the potential predictors for CSVD, with chronic gastritis and its proxies as alternatives. Method Patients aged 18 years or older with indications for electronic gastroscopy were enrolled. Presence of CSVD was evaluated with brain magnetic resonance imaging (MRI) results. Degree of CSVD was scored according to established criteria. Logistic regression analysis was used for identifying possible risk factors for CSVD. Results Of the 1191 enrolled patients, 757 (63.6%) were identified as with, and 434 (36.4%) as without CSVD. Multivariate analysis indicated that patients with chronic atrophic gastritis had an increased risk for CSVD than those without (adjusted odds ratio = 1.58; 95% CI, 1.08–2.32; P
Databáze: Directory of Open Access Journals
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