Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections

Autor: Pinkus Tober-Lau, Henning Gruell, Kanika Vanshylla, Willi M. Koch, David Hillus, Philipp Schommers, Isabelle Suárez, Norbert Suttorp, Leif Erik Sander, Florian Klein, Florian Kurth
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 28, Iss 5, Pp 1050-1052 (2022)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2805.220271
Popis: To determine neutralizing activity against the severe acute respiratory syndrome coronavirus 2 ancestral strain and 4 variants of concern, we tested serum from 30 persons with breakthrough infection after 2-dose vaccination. Cross-variant neutralizing activity was comparable to that after 3-dose vaccination. Shorter intervals between vaccination and breakthrough infection correlated with lower neutralizing titers.
Databáze: Directory of Open Access Journals