| Autor: |
Masoud Khorshidi, Zohreh Sajadi Hazaveh, Malek Alimohammadi-kamalabadi, Sanaz Jamshidi, Omid Moradi Moghaddam, Beheshteh Olang, Sayeh Hatefi, Amirhossein Hosseini, Parsa Jamilian, Meysam Zarezadeh, Parichehr Kohansal, Javad Heshmati, Parmida Jamilian, Aliakbar Sayyari |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Nutrition Journal, Vol 22, Iss 1, Pp 1-11 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1475-2891 |
| DOI: |
10.1186/s12937-022-00826-5 |
| Popis: |
Abstract Purpose Dyslipidemia is considered as a known risk factor for cardiovascular disease. Yet various trials with wide ranges of doses and durations have reported contradictory results. We undertook this meta-analysis of randomized controlled trials (RCTs) to determine whether omega-3 supplementation can affect lipid profile in children and adolescents. Methods Cochrane Library, Embase, PubMed, and Scopus databases were searched up to March 2021. Meta-analysis was performed using random-effect method. Effect size was expressed as weighted mean difference (WMD) and 95% confidence interval (CI). Heterogeneity was assessed using the I 2 index. In order to identification of potential sources of heterogeneity, predefined subgroup and meta-regression analysis was conducted. Results A total of 14 RCTs with 15 data sets were included. Based on the combination of effect sizes, there was a significant reduction in TG levels (WMD: -15.71 mg/dl, 95% CI: -25.76 to -5.65, P=0.002), with remarkable heterogeneity (I2=88.3%, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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