The association between allergy and sinusitis: a cross-sectional study based on NHANES 2005–2006

Autor: Song Li, Chu-Jin Zhao, Hong-Li Hua, Yu-Qin Deng, Ze-Zhang Tao
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Allergy, Asthma & Clinical Immunology, Vol 17, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1710-1492
DOI: 10.1186/s13223-021-00642-2
Popis: Abstract Background The relationship between allergies and sinusitis, though extensively studied, remains poorly defined. While several studies proposed a cause-and-effect relationship between allergy and chronic sinusitis, several others reported the lack of any existing association. This study aimed to investigate the relationship between allergy and sinusitis. Methods We conducted a cross-sectional study using a representative sample of the US population from the National Health and Nutrition Examination Survey 2005‒2006 (n = 7244). A self-reported allergy questionnaire and total and allergen-specific IgE levels were used for analysis. Participants were divided into positive and negative allergy symptoms groups (PAS, NAS, respectively) to eliminate the influence of allergy symptoms on the apparent incidence of sinusitis. Pearson’s chi-square test and the linear regression analysis using Durbin Watson test were used for statistical analysis. Results Sinusitis incidence in the PAS group (22.4%; 521/2327) was significantly higher than that in the NAS group (7.1%; 348/4917) [odds ratios (OR) = 3.788, 95% confidence interval (CI) 3.272‒4.384, P
Databáze: Directory of Open Access Journals