| Autor: |
Owen Addis Jones, Ankana Tiwari, Tomisin Olukoga, Alex Herbert, Kok-Lung Chan |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-10938-y |
| Popis: |
The kinase PLK1 has important roles during cell division, including mitotic entry and bipolar spindle formation. Here, the authors show that PLK1 also functions in centromere protection, with loss leading to DNA unwinding by Bloom’s syndrome helicase and subsequent collapse of chromosome alignment. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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