Porto-sinusoidal vascular disorder in chronic HBV: A significant coexistence not to be overlooked

Autor: Pol Olivas, Valeria Perez-Campuzano, Lara Orts, Carla Montironi, Marta Magaz, Pablo Ruiz, Sarah Shalaby, Asunción Ojeda, Pau Rosich, Anna Baiges, Fanny Turon, Sabela Lens, Juan Carlos García Pagán, Virginia Hernández-Gea
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: JHEP Reports, Vol 6, Iss 3, Pp 100996- (2024)
Druh dokumentu: article
ISSN: 2589-5559
DOI: 10.1016/j.jhepr.2023.100996
Popis: Background & Aims: Porto-sinusoidal vascular disorder (PSVD) encompasses a group of liver diseases with vascular abnormalities that can cause portal hypertension in the absence of cirrhosis. The new diagnostic criteria allow for coexistence with other liver diseases, however its relationship with chronic hepatitis B (CHB) remains unclear. This study aimed to assess HBV prevalence in a PSVD cohort and evaluate its clinical impact. Methods: This retrospective study was conducted on patients with PSVD at Hospital Clínic Barcelona. HBV serology was evaluated, and patients were categorized into HBV chronic infection, past infection, or no HBV exposure. Clinical characteristics and outcomes were compared. Results: We included 155 patients with PSVD. Prevalence of CHB and past HBV infection in patients with PSVD was higher than in the general population (5.8% vs. 0.5%, p
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