An economic evaluation of fine-needle cytology as the primary diagnostic tool in the diagnosis of lymphadenopathy

Autor: Cavallo Monica, Ciliberti Valeria, Maffei Elisabetta, Serio Bianca, Sabbatino Francesco, Zeppa Pio, Caputo Alessandro
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Open Medicine, Vol 18, Iss 1, Pp 2103-10 (2023)
Druh dokumentu: article
ISSN: 2391-5463
DOI: 10.1515/med-2023-0719
Popis: Fine-needle aspiration cytology (FNAC) is commonly used to obtain a pre-surgical pathological diagnosis in many organs, but its cost-effectiveness in lymphadenopathy has not been studied yet. We calculated the cost and diagnostic accuracy of a diagnostic algorithm that uses FNAC as a first-line procedure and compared it to a purely surgical approach in 545 consecutive lymphadenopathies. In 74% of the cases, FNAC alone can obtain a sufficiently detailed diagnosis, avoiding the surgical biopsy. In doing so, the average cost of diagnosis is cut to less than one-third, the patient avoids an invasive procedure and the diagnosis is reached earlier. In conclusion, the systematic use of lymph node-FNAC in the initial assessment of lymphadenopathy is clinically and economically advantageous as it avoids surgical biopsies in cases where cytology can suffice.
Databáze: Directory of Open Access Journals