The antioxidant status of coenzyme Q10 and vitamin E in children with type 1 diabetes

Autor: Usama M. Alkholy, Nermin Abdalmonem, Ahmed Zaki, Mohamed A. Elkoumi, Mustafa I. Abu Hashim, Maha A.A. Basset, Hossam E. Salah
Jazyk: portugalština
Rok vydání: 2019
Předmět:
Zdroj: Jornal de Pediatria (Versão em Português), Vol 95, Iss 2, Pp 224-230 (2019)
Druh dokumentu: article
ISSN: 2255-5536
DOI: 10.1016/j.jpedp.2018.03.002
Popis: Objective: The purpose of this study was to evaluate the antioxidant status of plasma vitamin E and plasma and intracellular coenzyme Q10 in children with type 1 diabetes. Method: This case–control study was conducted on 72 children with type 1 diabetes and compared to 48 healthy children, who were age, sex, and ethnicity‐matched. The diabetic children were divided according to their glycosylated hemoglobin (A1c %) into two groups: poor and good glycemic control groups. All children underwent full history taking, clinical examination, and laboratory measurement of complete blood count, A1c %, plasma cholesterol, triglycerides, and vitamin E levels and coenzyme Q10 levels in plasma, erythrocytes, and platelets. Results: Children with poor glycemic control showed significantly higher plasma vitamin E, coenzyme Q10, triglycerides, low‐density lipoproteins, waist circumference/height ratio, cholesterol levels, and lower high‐density lipoproteins and platelet coenzyme Q10 redox status in comparison to those with good glycemic control and the control group (p
Databáze: Directory of Open Access Journals