Single particle cryo-EM structure of the outer hair cell motor protein prestin

Autor: Carmen Butan, Qiang Song, Jun-Ping Bai, Winston J. T. Tan, Dhasakumar Navaratnam, Joseph Santos-Sacchi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-27915-z
Popis: Prestin, expressed in outer hair cell (OHC), belongs to the Slc26 transporter family and functions as a voltage-driven motor that drives OHC electromotility. Here, the authors report cryo-EM structure and characterization of gerbil prestin, with insights into its mechanism of action.
Databáze: Directory of Open Access Journals