'Honeycomb' appearance in large-duct type pancreatic ductal adenocarcinoma: Case report with radiologic–pathologic correlation

Autor: Ayaka Hara, MD, Yasunari Yamada, MD, Kengo Fukuzawa, MD, Mitsuteru Motomura, MD, Yusuke Kuboyama, MD, Kazuhito Sakata, MD, Ryo Takaji, MD, Yoshiki Asayama, MD, Hajime Takaki, MD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Radiology Case Reports, Vol 17, Iss 9, Pp 3439-3445 (2022)
Druh dokumentu: article
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2022.06.047
Popis: Large-duct type pancreatic ductal adenocarcinoma (PDA) is a rare morphologic variant forming large duct elements. This case report, to our knowledge, is the first report of a large-duct type PDA with a “honeycomb” appearance resembling a serous cystic neoplasm (SCN) on CT and MRI. The patient is an 82-year-old woman who presented with upper abdominal pain. Dynamic contrast-enhanced CT revealed a multilocular cyst with honeycomb loculi, in which the cyst walls showed gradual enhancement. On T2-weighted MRI, the mass displayed inhomogeneous hyperintensity characterized by a honeycomb appearance with irregular and thick hypointense cyst walls. The patient underwent distal pancreatectomy; histopathological diagnosis was large-duct type PDA. Although the imaging features of large-duct type PDA may resemble those of SCN, this distinction between PDA and SCN is important because the treatment options are very different.
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