Efferent Treatment for Critical Conditions
| Autor: | S. E. Khoroshilov, A. V. Nikulin |
|---|---|
| Jazyk: | English<br />Russian |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Общая реаниматология, Vol 8, Iss 4 (2012) |
| Druh dokumentu: | article |
| ISSN: | 1813-9779 2411-7110 |
| DOI: | 10.15360/1813-9779-2012-4-30 |
| Popis: | Endogenous intoxication as a typical pathological process has been and remains one of the key problems in virtually all fields of medicine and mainly in reanimatology. Accumulation of endogenous toxic substances is an integral component of any critical condition and accompanies severe injury, generalized infections, abdominal organ derangement. Loss of the function of detoxifying systems in multiple organ dysfunction leads to progressive endotoxicosis and worsening gas exchange disorders, including detoxification in the organs themselves, thus closing the vicious circle of tanatogenesis. Endogenous intoxication is a multidisciplinary problem that is the area of many different fields of practical medicine, experimental pathophysiology, and biomedical technology. Thus, current efferent therapeutic techniques for critical conditions and extracorporeal detoxification in particular are being introduced into clinical practice. The V. A. Negovsky Research Institute of General Reanimatology, Russian Academy of Medical Sciences, has been studying the theoretical and applied issues concerning the problem of endotoxicosis for many years. This review attempts to generalize the main results the Institute’s activity in this area. Key words: endogenous intoxication, efferent therapy, detoxification. |
| Databáze: | Directory of Open Access Journals |
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