Significance of Morphometric Evaluation of PreMalignant and Malignant Lesions of Uterine Cervix: A Cross-sectional Analytical Study
| Autor: | Hajra K Mehdi, Kalyani Raju, SR Sheela |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 13, Iss 4, Pp EC05-EC07 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2249-782X 0973-709X |
| DOI: | 10.7860/JCDR/2019/40185.12773 |
| Popis: | Introduction: Morphometric analysis of various parameters of the cells is done to classify the lesion as benign or malignant. It is an objective assessment which reduces the variability due to subjective visual assessment. Authors have done the nuclear morphometric analysis in ectocervix and endocervix tissue sections. Aim: To evaluate the significance and utility of nuclear morphometry in pre-malignant and malignant lesions of uterine cervix. Materials and Methods: This was a retrospective crosssectional study done on 120 cases of cervix which were categorised histomorphologically into normal ectocervix, chronic cervicitis, Low-Grade Squamous Intraepithelial Lesion (LSIL), High-Grade Squamous Intraepithelial Lesion (HSIL), Squamous Cell Carcinoma (SCC), normal endocervix, chronic endocervicitis, Low-Grade Cervical Glandular Intraepithelial Neoplasia (LCGIN), Adenocarcinoma In Situ (AIS) and adenocarcinoma. The quantitative nuclear morphometry analysis was done and entered in Microsoft Excel sheet. Statistical analysis was done by using SPSS software 22.0 version. The p-value |
| Databáze: | Directory of Open Access Journals |
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