The relationship between obstructive sleep apnea and diabetic retinopathy in type 2 diabetes patients, Zagazig University Hospitals, Egypt

Autor: Sameh Embarak, Ahmad Abbas, Haitham Y Al-Nashar, Salama E Farag
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Egyptian Journal of Chest Disease and Tuberculosis, Vol 68, Iss 3, Pp 290-295 (2019)
Druh dokumentu: article
ISSN: 0422-7638
2090-9950
DOI: 10.4103/ejcdt.ejcdt_160_18
Popis: Background and objective Obstructive sleep apnea (OSA) and type 2 diabetes mellitus (T2DM) commonly coexist. Both could be associated with a number of pathophysiological derangements involved in the development of diabetic retinopathy (DR). So, the aim of this study was to assess the possible association between OSA and DR. Patients and methods This is a cross-sectional observational study that was conducted on patients with T2DM. Two-field 45°-digital retinal images for each eye were used to evaluate DR and graded according to the English National Screening Program guidelines. OSA was evaluated on the basis of an inpatient overnight sleep study (polysomnography) using a computerized polysomnogram device. Results This work recruited 110 patients. OSA was observed in 60% (66 patients). OSA was found to be independently associated with both advanced DR [preprolifrative (R2) or proliferative (R3)] (odds ratio=6.29; 95% confidence interval: 1.08–6.65; P=0.04) and maculopathy (odds ratio=12.92; 95% confidence interval: 3.97–4.79; P
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