| Autor: |
Jun Young Choi, Ji Won Park, Ji Eun Kim, Jin Ju Park, Mi Rim Lee, Bo Ram Song, Mi Ju Kang, Dae Youn Hwang |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Laboratory Animal Research, Vol 34, Iss 3, Pp 101-110 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2233-7660 |
| DOI: |
10.5625/lar.2018.34.3.101 |
| Popis: |
Abstract The butanol extract of Asparagus cochinchinensis roots fermented with Weissella cibaria (BAfW) significantly suppressed the inflammatory response induced by lipopolysaccharide (LPS) treatment in RAW264.7 cells. To investigate the dose dependence and durability of BAfW on the anti-asthma effects, alterations in key parameters were measured in ovalbumin (OVA)-challenged Balb/c mice treated with the different doses of BAfW at three different time points. The number of immune cells, OVA-specific IgE level, thickness of respiratory epithelium and mucus score decreased significantly in a dose-dependent manner in response to treatment with 125 to 500 mg/kg BAfW (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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