Prevalence and associated factors of airway hyper- responsiveness in children with recurrent chronic cough
| Autor: | I Gusti Agung Ngurah Sugitha Adnyana, Putu Suwendra, Hendra Santoso |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Paediatrica Indonesiana, Vol 44, Iss 5, Pp 181-7 (2016) |
| Druh dokumentu: | article |
| ISSN: | 0030-9311 2338-476X |
| DOI: | 10.14238/pi44.5.2004.181-7 |
| Popis: | Background Airway hyper-responsiveness (AH) is a common char- acteristic of asthma. Patient who has recurrent chronic cough with AH is commonly referred as “cough variant asthma”. Histamine provocation test should be performed to determine whether a pa- tient has “cough variant asthma” or recurrent viral bronchitis. Objective To determine AH prevalence in children with recurrent chronic cough and factors associated with it. Methods A cross sectional study was conducted on 6-12 year-old children with recurrent chronic cough at the Pediatrics Outpatient Clinic, Sanglah Hospital Denpasar from September 2002 until June 2003 Results Twenty one out of 64 (33%) subjects suffering from recur- rent chronic cough without wheezing had AH. Associated factors significantly associated with AH were age, allergic rhinitis, pater- nal and maternal history of atopy, passive smoking, use of mos- quito-coil, positive skin prick test, and eosinophilia. Spearman cor- relation analysis between associated factors and AH showed that positive skin prick test and passive smoking were moderately cor- related with AH (r=0.56, p |
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