| Autor: |
Bing Zheng, Zhiyuan Li, Feipeng Liu, Yanhua Wu, Junjian Shen, Qinghua Bian, Shicong Hou, Ming Wang |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Molecules, Vol 18, Iss 12, Pp 15422-15433 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/molecules181215422 |
| Popis: |
The enantioselective addition of phenylethynylzinc to aldehydes catalyzed by a series of cyclopropane-based amino alcohol ligands 7 was investigated. The reactions afforded chiral propargylic alcohols in high yields (up to 96%) and with excellent enantioselectivities (up to 98% ee) under mild conditions. Furthermore, studies on the structural relationship show that the matching of the chiral center configuration is crucial to obtain the high enantioselectivity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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