Mechanical responses of the bio-nano interface: A molecular dynamics study of graphene-coated lipid membrane

Autor: Zhigong Song, Yanlei Wang, Zhiping Xu
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Theoretical and Applied Mechanics Letters, Vol 5, Iss 6, Pp 231-235 (2015)
Druh dokumentu: article
ISSN: 2095-0349
DOI: 10.1016/j.taml.2015.11.003
Popis: Bio-nano interfaces between biological materials and functional nanodevices are of vital importance in relevant energy and information exchange processes, which thus demand an in-depth understanding. One of the critical issues from the application viewpoint is the stability of the bio-nano hybrid under mechanical perturbations. In this work we explore mechanical responses of the interface between lipid bilayer and graphene under hydrostatic pressure or indentation loads. We find that graphene coating provides remarkable resistance to the loads, and the intercalated water layer offers additional protection. These findings are discussed based on molecular dynamics simulation results that elucidate the molecular level mechanisms, which provide a basis for the rational design of bionanotechnology-enabled applications such as biomedical devices and nanotherapeutics.
Databáze: Directory of Open Access Journals