Manasamitra Vatakam on Scopolamine-Induced Amnesia in Female Wistar Rats

Autor: Sankar A, Kandasamy Deepa, Radhakrishan Anjuna, Janaki C. S, Sheriff Dhastangir, Prabhu K
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss 6, Pp 1824-1828 (2024)
Druh dokumentu: article
ISSN: 0976-4879
0975-7406
DOI: 10.4103/jpbs.jpbs_9_24
Popis: BackgroundNeurodegenerative diseases induce amnesia, and effective treatment is still elusive. Aims and Objectives: The present study highlights the ameliorating effects of Manasa Mitra Vatakam (MMV) using behavioral parameters on scopolamine-induced memory loss in female Wistar rats. Materials and MethodsMMV was compared with DPZ as a standard in the present study to determine the behavioral parameters through elevated plus maze (Hebb William maze/rectangular maze)and locomotor activity in scopolamine-induced memory loss in female Wistar rats. Results and DiscussionThe results of the study illustrate the effectiveness of MMV in reversing memory dysfunction and memory-enhancing effects. ConclusionThe study paves the way for exploring research in CNS disorders and its potential application in drug-induced neurotoxicity.
Databáze: Directory of Open Access Journals