Manasamitra Vatakam on Scopolamine-Induced Amnesia in Female Wistar Rats
Autor: | Sankar A, Kandasamy Deepa, Radhakrishan Anjuna, Janaki C. S, Sheriff Dhastangir, Prabhu K |
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Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss 6, Pp 1824-1828 (2024) |
Druh dokumentu: | article |
ISSN: | 0976-4879 0975-7406 |
DOI: | 10.4103/jpbs.jpbs_9_24 |
Popis: | BackgroundNeurodegenerative diseases induce amnesia, and effective treatment is still elusive. Aims and Objectives: The present study highlights the ameliorating effects of Manasa Mitra Vatakam (MMV) using behavioral parameters on scopolamine-induced memory loss in female Wistar rats. Materials and MethodsMMV was compared with DPZ as a standard in the present study to determine the behavioral parameters through elevated plus maze (Hebb William maze/rectangular maze)and locomotor activity in scopolamine-induced memory loss in female Wistar rats. Results and DiscussionThe results of the study illustrate the effectiveness of MMV in reversing memory dysfunction and memory-enhancing effects. ConclusionThe study paves the way for exploring research in CNS disorders and its potential application in drug-induced neurotoxicity. |
Databáze: | Directory of Open Access Journals |
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