Quality Assessment and Relevant Clinical Impact of Randomized Controlled Trials of Varicocele: Next Step to Good-Quality Randomized Controlled Trial of Varicocele Treatment
Autor: | Kyu Shik Kim, Jae Hoon Chung, Hyung Joon Park, Woo Jong Shin, Bum Hyun Lee, Seung Wook Lee |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | The World Journal of Men's Health, Vol 40, Iss 2, Pp 290-298 (2022) |
Druh dokumentu: | article |
ISSN: | 2287-4208 2287-4690 |
DOI: | 10.5534/wjmh.200167 |
Popis: | Purpose: To assess the quality of randomized controlled trials (RCTs) on varicocele published from 1979 to 2017. Materials and Methods: We searched for original RCT on varicocele published between 1979 and 2017. Jadad scale, van Tulder scale, and Cochrane Collaboration Risk of Bias Tool were used to analyze RCT quality over time. Effects on RCT quality including funding source, Institutional Review Board (IRB) approval, and intervention were assessed. Treatment parameters of varicocele were also analyzed. Results: Blinding and allocation concealment were described in 25.9% and 9.4% of RCT, respectively. Both tended to increase and a sharp dip in allocation concealment was observed in 2010–2017. Jadad scores increased steadily from 1979 to 2017 (1.28±0.59 to 2.19±1.10, p |
Databáze: | Directory of Open Access Journals |
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