EXTRACTION, CHARACTERISATION, ANTIMICROBIAL AND ANTIOXYDANT ACTIVITY OF THE ESSENTIAL OIL OF SALVIA CHUDAEI BATT AND TRAB: ENDEMIC SPECIES OF CENTRAL SAHARA
| Autor: | Dif Sabrina, Khali Mustapha |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Natural Resources and Sustainable Development, Vol 13, Iss 1, Pp 85-98 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2066-6276 2601-5676 |
| DOI: | 10.31924/nrsd.v13i1.119 |
| Popis: | The actuel challenges focuses on the enhancement of resources and biodiversity for the Algerian flora, It primoedial to give more of interest to the endemic species, wich remain rarely explored despite the fact they face the imminent risk of extinction. In this study, we aimed to characteris the phytochemical and pharmacological of the volatile fraction of the Salvia chudaei Batt and Trab aerial pieces. This is an endemic species of central Sahara. To the best knowledge of the authors, our study is aismong the first to study such species. Essential oil extraction was performed by hydro distillation accompanied by chromatographic CG/MS study. The antioxidant strength of this essential oil was determined by the DPPH Test (2, 2-diphenyl-1-picrylhydrazyl); FRAP Test (Ferric Reducing Ability of Plasma) and peroxidation of linoleic acid test. The antimicrobial activity was processed by method of diffusion in solid media and the determination of the minimum inhibitory concentration. It was tested on 12 bacterial strains (Gram, Gram +), two yeasts and two fungal strains. The main results obtained by CG/MS analysis counts a total of 26 compounds which isobornyl acetate, alpha pinen, elemol and trans-caryophyllene are described as majore elements. The essential oil demonstrated a notable inhibition of the growth of Gram + tested bacteria, Bacillus subtilis, Staphylococcus aureus, Staphylococcus epidermidis, Enterococus faecalis and Sarcina lutea. The minimum CMI inhibitors found varying from 0.5 to 2.5 mg. Interestingly, the essential oil didn’t shown any significant action on Gram- bacteria. The analysis of the antioxidant power revealed a strong anti-radical potential (IC50 = 932.1 μg/ml), high peroxide inhibition (91.7 %) and modest reductive power (59.96 %). The results indicated that essential oil of Salvia chudaei has a significant potential as an antimicrobial and antioxidant agent applicable in the pharmaceutical and agri-food fields. |
| Databáze: | Directory of Open Access Journals |
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