The Association between the Hypochloremia and Mortality in Intensive Care Unit (ICU) Patients with Chronic Heart Failure

Autor: Jinping Zhang, Zhenze Yu, Binghua Zhu, Jianxin Ma
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Vascular Diseases, Vol 2, Iss 2, Pp 188-196 (2023)
Druh dokumentu: article
ISSN: 2813-2475
DOI: 10.3390/jvd2020013
Popis: Objective: To explore the association between hypochloremia and mortality in critically ill patients with chronic heart failure (CHF). Methods: This is a retrospective cohort study from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database of patients with CHF diagnosed according to ICD-9 or ICD-10. Patients were divided into three groups according to serum chloride values. A multivariable logistic regression analysis was used to investigate the relationship between hypochloremia and short-term mortality. Results: A total of 2103 patients with CHF were enrolled in our study. The 30-day mortality was 6.7%. After adjusting for confounders, the 30-day mortality risks of the hypochloremia group were significantly higher than that of the group with normal serum chloride (OR 2.23, 95% CI 1.27–3.92, p = 0.005). Hypochloremia was consistently associated with increased mortality in patients that were older or had sepsis. Conclusion: Hypochloremia is associated with increased mortality in intensive care patients critically ill with CHF.
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