Comparison of Endurance Training and Overtraining on the Balance of Th1 / Th2 in Male Wistar Rats
| Autor: | O Salehian, R Soori, AA Ravasi, S Choobine |
|---|---|
| Jazyk: | perština |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Armaghane Danesh Bimonthly Journal, Vol 21, Iss 5, Pp 481-491 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1728-6514 1728-6506 |
| Popis: | Background & aim: The immune system is involved in numerous activities including inflammatory and anti-inflammatory activities. The activities associated with the production of Interferonγ and Interleukin-4. The present study investigated the effect of endurance training on the balance of these two cytokines pays more. Methods: In the present study, 30 rats were selected and divided into 3 groups of 10: control, endurance and overtraining exercise. Endurance training protocol and overtraining were done for 12 weeks. Endurance training was done with the speed of 10 m/min in first week and 23m/min in last week. Overtraining protocol was done with the speed of 15 m/min in first week and 25 m/min in last week. Speleenectomy was done after interval training protocol, and then Interleukin 4 (IL4) and Interferon γ (IFNγ) were evaluated by the Eliza method. One-way ANOVA and Tukey post hoc test was used for data analysis. Results: The results showed a significant increase in the amount of (IFNγ) and a decrease in the levels of IL4 in endurance training group (p=0.01). The results also exposed an increase in levels of IL4 and decrease IFNγ levels in overtraining group which was significant (p=0.01). Conclusion: It can be concluded that the response to endurance training the amount of IFNγ and in response to overtraining the level of IL-4 was increased. |
| Databáze: | Directory of Open Access Journals |
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