Multiple resistance in equine cyathostomins: a case study from military establishments in Rio Grande do Sul, Brazil

Autor: Alexandra Geyer Flores, Vanessa Osmari, Fernanda Ramos, Camila Balconi Marques, Denise Jaques Ramos, Sônia de Avila Botton, Fernanda Silveira Flores Vogel, Luís Antônio Sangioni
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2020
Předmět:
Zdroj: Revista Brasileira de Parasitologia Veterinária, Vol 29, Iss 3 (2020)
Druh dokumentu: article
ISSN: 1984-2961
DOI: 10.1590/s1984-29612020086
Popis: Abstract Semi-intensive equine breeding system favors gastrointestinal nematode infections. The treatment of these infections is based on the use of anthelmintics. However, the inappropriate use of these drugs has led to parasitic resistance to the available active principles. The objective of this study was to evaluate the efficacy of the main classes of antiparasitic (ATP) used in control in adult and young animals, including: benzimidazoles (fenbendazole), pyrimidines (pyrantel pamoate), macrocyclic lactones (ivermectin and moxidectin), as well as the combination of active ingredients (ivermectin + pyrantel pamoate). The study was carried out in two military establishments, located in Rio Grande do Sul (RS), from January to December, 2018. The intervals between the treatments of the animals were performed from 30 to 90 days. Coproparasitological evaluations were determined by the egg count reduction in the faeces. Cyatostomine larvae were identified in pre and post-treatment cultures. The results demonstrated the multiple parasitic resistance of cyathostomins to fenbendazole, moxidectin in young animals, and to fenbendazole, pyrantel pamoate in adult animals. Thus, it is necessary to define or diagnose parasitic resistance to assist in the creation of prophylactic parasitic control, using suppressive treatment with ATP associated with integrated alternatives. The progress of parasitic resistance can be slowed.
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