Resolution of pulmonary artery thrombosis in patients with moderate COVID-19 disease

Autor: Grazia Zanframundo, Alessandro Graziani, Barbara Caroli, Francesco Palmese, Cristian Bertoldi, Pierluigi Cataleta, Maria Teresa Minguzzi, Ludovico Graziani, Marco Domenicali
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 4, Pp 470-472 (2021)
Druh dokumentu: article
ISSN: 2000-9666
20009666
DOI: 10.1080/20009666.2021.1921908
Popis: Novel Coronavirus disease (COVID-19) has been widely described as the cause for a proinflammatory and hypercoagulable state. The inflammatory process involving the alveolar vascular endothelium in the respiratory system, is a determining factor for the onset of primary Pulmonary Artery Thrombosis (PAT) even in patients with heparin prophylactic treatment. Little is known about the efficacy of the anticoagulant therapy during the course of PAT caused by COVID-19. In this paper we describe the results obtained in patients with moderate COVID-19 disease, previously threated with prophylactic enoxaparin, who then received full Anticoagulant treatment after diagnosis of PAT. After three months Computed Tomography Pulmonary Angiography demonstrated a complete resolution of the vascular obstructive lesions in all patients, while all the coagulation tests were normal.
Databáze: Directory of Open Access Journals
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