Genetic Insights into Congenital Cardiac Septal Defects—A Narrative Review

Autor: Jorge L. Cervantes-Salazar, Nonanzit Pérez-Hernández, Juan Calderón-Colmenero, José Manuel Rodríguez-Pérez, María G. González-Pacheco, Clara Villamil-Castañeda, Angel A. Rosas-Tlaque, Diego B. Ortega-Zhindón
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Biology, Vol 13, Iss 11, p 911 (2024)
Druh dokumentu: article
ISSN: 2079-7737
DOI: 10.3390/biology13110911
Popis: Congenital heart diseases (CHDs) are a group of complex diseases characterized by structural and functional malformations during development in the human heart; they represent an important problem for public health worldwide. Within these malformations, septal defects such as ventricular (VSD) and atrial septal defects (ASD) are the most common forms of CHDs. Studies have reported that CHDs are the result of genetic and environmental factors. Here, we review and summarize the role of genetics involved in cardiogenesis and congenital cardiac septal defects. Moreover, treatment regarding these congenital cardiac septal defects is also addressed.
Databáze: Directory of Open Access Journals