Prevalence of low trabecular bone score and its association with disease severity and activity in patients with axial spondyloarthritis

Autor: Pannarat Saisirivechakun, Ajanee Mahakkanukrauh, Chatlert Pongchaiyakul, Trirat Boonya-ussadorn, Pongthorn Narongroeknawin, Rattapol Pakchotanon, Paijit Assavatanabodee, Sumapa Chaiamnuay
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-023-43321-5
Popis: Abstract Axial spondyloarthritis (axSpA) increases the risk of osteoporosis and vertebral fractures. Bone mineral density (BMD) measured by dual X-ray absorptiometry (DXA) has limitations in axSpA patients. Trabecular bone score (TBS) indirectly assesses bone microarchitecture and can be used to predict fracture risk. However, few studies have investigated the role of TBS in axSpA patients. The objective of this study were to compare TBS between axSpA patients and 1:1 sex- and age-matched healthy volunteers and determine factors associated with low TBS in axSpA patients. A cross-sectional study was conducted in two tertiary-care hospitals. A total of 137 axSpA patients and healthy volunteers were enrolled. Demographics, disease characteristics, and risk factors for osteoporosis were recorded. TBS, BMD at the lumbar spine, hip, and vertebral fractures were assessed by DXA. Low TBS was defined as a TBS value
Databáze: Directory of Open Access Journals
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