A Proof of Principle Study of the Terminal Sterilization of Prefilled Syringes Using A Water Cascade Process

Autor:	Drost-Wijnne Anne J.A., Van Wezel Ralph A.C., Deenen Maarten J., Van Doornmalen Gomez Hoyos Joost P.C.M., Grouls René J.E.
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	ready-to-administer compounding sterilization water cascade sterilization prefilled syringe Therapeutics. Pharmacology RM1-950 Pharmaceutical industry HD9665-9675
Zdroj:	Pharmaceutical Technology in Hospital Pharmacy, Vol 3, Iss 4, Pp 191-198 (2018)
Druh dokumentu:	article
ISSN:	2365-2411 2365-242X 2018-0020
DOI:	10.1515/pthp-2018-0020
Popis:	A new development in drug compounding is the production of ready-to-administer sterilized prefilled syringes. A challenge with these syringes is the method of terminal sterilization. There is no information available whether water cascade sterilization is a suitable method. We investigated the effect of this sterilization method on cyclic olefin (co)polymer (CCP/COC) syringes.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/4b5664d526bb4c22b3ad154d9c449d5b Zobrazit plný text záznamu View record in DOAJ