Induced pluripotent stem cell line, ICAGi001-A, derived from human skin fibroblasts of a patient with 2p25.3 deletion and 2p25.3-p23.3 inverted duplication

Autor: A.A. Khabarova, I.E. Pristyazhnyuk, T.V. Nikitina, T.A. Gayner, N.B. Torkhova, N.A. Skryabin, A.A. Kashevarova, N.P. Babushkina, Zh.G. Markova, M.E. Minzhenkova, L.P. Nazarenko, N.V. Shilova, A.R. Shorina, I.N. Lebedev, O.L. Serov
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Stem Cell Research, Vol 34, Iss , Pp - (2019)
Druh dokumentu: article
ISSN: 1873-5061
DOI: 10.1016/j.scr.2018.101377
Popis: Skin fibroblasts from a patient with developmental delay and chromosome 2p25.3 deletion syndrome were reprogrammed into induced pluripotent stem cells (iPSCs) and the clonal stem cell line ICAGi001-A (iTAF9-11) was established. ICAGi001-A pluripotency was demonstrated in vitro by three germ layer differentiation capacity. This line is a good model for studying of the developmental delay and brain disorder.
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