Oxaliplatin-Induced Pulmonary Toxicity in Gastrointestinal Malignancies: Two Case Reports and Review of the Literature
| Autor: | Mor Moskovitz, Mira Wollner, Nissim Haim |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Case Reports in Oncological Medicine, Vol 2015 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2090-6706 2090-6714 |
| DOI: | 10.1155/2015/341064 |
| Popis: | Oxaliplatin is a common chemotherapy drug, used mainly for colon and gastric cancer. Most common side effects are peripheral sensory neuropathy, hematological toxicity, and allergic reactions. A less common side effect is pulmonary toxicity, characterized mainly by interstitial pneumonitis. The incidence of this side effect is unknown, but the toxicity can be fatal. Twenty-six cases of pulmonary toxicity have been described in the literature, seven in the setting of adjuvant treatment. We describe two fatal cases of pulmonary injury related to oxaliplatin and a review of the literature. |
| Databáze: | Directory of Open Access Journals |
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