Validation of Revised Chinese Version of PD-CRS in Parkinson’s Disease Patients

Autor: Yuyan Tan, Weiguo Liu, Juanjuan Du, Miaomiao Hou, Cuiyu Yu, Yang Liu, Shishuang Cui, Lei Yan, Yizhou Lu, Hong Lv, Lijun Han, Xi Wang, Shengyu Zha, Xiaoguang Luo, Huidong Tang, Shengdi Chen
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Parkinson's Disease, Vol 2020 (2020)
Druh dokumentu: article
ISSN: 2090-8083
2042-0080
DOI: 10.1155/2020/5289136
Popis: There is a high prevalence of mild cognitive impairment (MCI) and dementia in Parkinson’s disease (PD) patients, but a Chinese version of cognitive rating scale that is specific and sensitive to PD patients is still lacking. The aims of this study are to test the reliability and validity of a Chinese version of Parkinson’s disease-cognitive rating scale (PD-CRS), establish cutoff scores for diagnosis of Parkinson’s disease dementia (PDD) and PD with mild cognitive impairment (PD-MCI), explore cognitive profiles of PD-MCI and PDD, and find cognitive deficits suggesting a transition from PD-MCI to PDD. PD-CRS was revised based on the culture background of Chinese people. Ninety-two PD patients were recruited in three PD centers and were classified into PD with normal cognitive function (PD-NC), PD-MCI, and PDD subgroups according to the cognitive rating scale (CDR). Those PD patients underwent PD-CRS blind assessment by a separate neurologist. The PD-CRS showed a high internal consistency (Cronbach’s Alpha = 0.840). Intraclass Correlation coefficient (ICC) of test-retest reliability reached 0.906 (95% CI 0.860–0.935, p
Databáze: Directory of Open Access Journals
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