Proteotoxicity caused by perturbed protein complexes underlies hybrid incompatibility in yeast

Autor: Krishna B. S. Swamy, Hsin-Yi Lee, Carmina Ladra, Chien-Fu Jeff Liu, Jung-Chi Chao, Yi-Yun Chen, Jun-Yi Leu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-32107-4
Popis: Hybrid incompatibility can be an important element of reproductive isolation and speciation. Using chromosome replacement lines of yeast, the authors show that perturbed proteostasis caused by destabilized hybrid protein complexes may represent a general mechanism of hybrid incompatibility.
Databáze: Directory of Open Access Journals