| Autor: |
Marcelo Santos Sampaio, Grigoriy Alexander Shekhtman, Mandana Rastegar, Richard Michael Treger, Glenn Tetsu Nagami, Jonathan Eric Zuckerman |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Human Pathology Reports, Vol 26, Iss , Pp 300563- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2772-736X |
| DOI: |
10.1016/j.hpr.2021.300563 |
| Popis: |
Introduction: Syphilis is a sexually transmitted disease caused by the bacterium Treponema Pallidum and has a diverse clinical presentation, including nephropathies, the most common of which is membranous nephropathy. Crescentic glomerulonephritis is not typically considered to be a manifestation of Syphilis associated renal disease. Case presentation: Here we describe an unusual case of crescentic glomerulonephritis associated with secondary syphilis resulting in a rapidly progressing glomerulonephritis presentation requiring hemodialysis. The patient was treated with Penicillin G and intravenous solumedrol. The patient’s kidney function recovered and several months after presentation the patient was asymptomatic off hemodialysis with a serum creatinine of 1.54 mg/dL. Discussion/conclusion: Secondary syphilis rarely presents with rapidly progressive glomerulonephritis. This report is only the third such case reported to date of a diffuse necrotizing/crescentic glomerulonephritis resulting from a syphilis infection. As syphilis is on the rise, this report highlights an important differential diagnostic consideration for any necrotizing/crescentic glomerulonephritis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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