| Autor: |
Maurizio Di Marco, Sabrina Scilletta, Nicoletta Miano, Nicola Marrano, Annalisa Natalicchio, Francesco Giorgino, Stefania Di Mauro, Agnese Filippello, Alessandra Scamporrino, Paola Tribulato, Giosiana Bosco, Francesco Di Giacomo Barbagallo, Roberto Scicali, Agostino Milluzzo, Teresa Ballirò, Lucia Frittitta, Pietro Castellino, Francesco Purrello, Salvatore Piro, Antonino Di Pino |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-11 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1475-2840 |
| DOI: |
10.1186/s12933-023-02065-2 |
| Popis: |
Abstract Background In the last years, the classical pattern of diabetic kidney disease (DKD) has been partially overcome, because of the uncovering of a new DKD phenotype with significant renal dysfunction without presence of albuminuria: the non-albuminuric DKD (NA-DKD). To date, the cardiovascular risk associated with this phenotype is still debated. We investigated the cardiovascular risk and renal injury profile of NA-DKD subjects in comparison with other DKD phenotypes. Methods Pulse wave velocity (PWV), intima-media thickness, presence of carotid atherosclerotic plaque, renal resistive index (RRI), and a panel of urinary biomarkers of kidney injury were evaluated in 160 subjects with type 2 diabetes, stratified according to estimated glomerular filtration rate (eGFR) and urinary albumin to creatinine ratio (UACR) into four groups: controls (UACR |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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