Insulin Therapy: 'When Saviour Turns Hostile'

Autor: Dhanya Soodhana Mohan, Vani Hebbal Nagarajappa, Santhosh Olety Sathyanarayana, Sahana M. Srinivas, Raghupathy Palany
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Dubai Diabetes and Endocrinology Journal, Pp 1-4 (2022)
Druh dokumentu: article
ISSN: 2673-1797
2673-1738
00052256
DOI: 10.1159/000522562
Popis: Insulin is the cornerstone of type 1 diabetes mellitus (T1DM) treatment. Insulin allergy in patients with T1DM on insulin is an uncommon problem that might manifest itself as immediate or delayed symptoms after injections. We present 2 cases: the first is a 17-year-old girl who was diagnosed with T1DM at the age of 14 and has had several skin lesions at injection sites over the past 2 months that have not responded to antibiotics. The second case involves a 4-year-old boy who was diagnosed with T1DM at the age of 15 months and had non-tender, erythematous, and indurated lesions. Insulin hypersensitivity was detected in both cases, thus newer analogues were administered instead of regular and isophane insulin, and the lesions dramatically reduced.
Databáze: Directory of Open Access Journals