Role and significance of asprosin in feeding behaviour and metabolism

Autor: Rustam H. Salimkhanov, Vladislav R. Sharifullin, Yulia R. Kushnareva, Azamat Kh. Kade, Pavel P. Polyakov
Jazyk: ruština
Rok vydání: 2020
Předmět:
Zdroj: Кубанский научный медицинский вестник, Vol 27, Iss 1, Pp 96-104 (2020)
Druh dokumentu: article
ISSN: 1608-6228
2541-9544
DOI: 10.25207/1608-6228-2020-27-1-96-104
Popis: This article presents a review of available information on asprosin — a hormone of white adipose tissue discovered in 2016. The history of its discovery, as well as its action mechanisms and main targets are examined. Changes in the plasma level of asprosin under some pathological conditions are analysed. The importance of studying asprosin is determined by its functions: asprosin regulates physiological processes during fasting and plays an important role in the development of metabolic disorders, such as insulin resistance. There are relatively few studies concerned with asprosin; however, this hormone can already be considered as a diagnostic marker and a potential target in the treatment of certain metabolic disorders, e.g. diabetes mellitus and obesity.
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