Epidemiology of paediatric gastrointestinal colonisation by extended spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolates in north-west Cambodia

Autor:	J. J. van Aartsen, C. E. Moore, C. M. Parry, P. Turner, N. Phot, S. Mao, K. Suy, T. Davies, A. Giess, A. E. Sheppard, T. E. A. Peto, N. P. J. Day, D. W. Crook, A. S. Walker, N. Stoesser
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Paediatric ESBL Carriage Cambodia Microbiology QR1-502
Zdroj:	BMC Microbiology, Vol 19, Iss 1, Pp 1-14 (2019)
Druh dokumentu:	article
ISSN:	1471-2180
DOI:	10.1186/s12866-019-1431-9
Popis:	Abstract Background Extended-spectrum cephalosporin resistance (ESC-R) in Escherichia coli and Klebsiella pneumoniae is a healthcare threat; high gastrointestinal carriage rates are reported from South-east Asia. Colonisation prevalence data in Cambodia are lacking. The aim of this study was to determine gastrointestinal colonisation prevalence of ESC-resistant E. coli (ESC-R-EC) and K. pneumoniae (ESC-R-KP) in Cambodian children/adolescents and associated socio-demographic risk factors; and to characterise relevant resistance genes, their genetic contexts, and the genetic relatedness of ESC-R strains using whole genome sequencing (WGS). Results Faeces and questionnaire data were obtained from individuals
Databáze:	Directory of Open Access Journals
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