Fatty liver in men is associated with high serum levels of small, dense low-density lipoprotein cholesterol

Autor: Hosoyamada Kaori, Uto Hirofumi, Imamura Yasushi, Hiramine Yasunari, Toyokura Eriko, Hidaka Yoshihiro, Kuwahara Tomomi, Kusano Ken, Saito Kazuto, Oketani Makoto, Ido Akio, Tsubouchi Hirohito
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Diabetology & Metabolic Syndrome, Vol 4, Iss 1, p 34 (2012)
Druh dokumentu: article
ISSN: 1758-5996
DOI: 10.1186/1758-5996-4-34
Popis: Abstract Aims Our study addressed potential associations between fatty liver and small, dense low-density lipoprotein cholesterol (sd-LDL-C) levels using a cross-sectional analysis. Methods We enrolled 476 male subjects. Serum sd-LDL-C concentrations were determined using precipitation assays. Results Subjects were divided into four groups based on triglyceride (TG) and LDL-C levels: A, TG Conclusions Fatty liver is a significant determinant of serum sd-LDL-C levels independent of the presence of obesity or hyperglycemia. Fatty liver may alter hepatic metabolism of TG and LDL-C, resulting in increased sd-LDL-C levels.
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