Histopathological categorization of desmoplastic reaction in gallbladder carcinoma: its relation to cancer invasiveness and prognostic utility

Autor:	Abir Baruah, Geet Bhuyan, Projnan Saikia
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Gallbladder Carcinoma Desmoplasia Prognosis Invasiveness Surgery RD1-811 Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Egyptian Liver Journal, Vol 13, Iss 1, Pp 1-7 (2023)
Druh dokumentu:	article
ISSN:	2090-6226
DOI:	10.1186/s43066-023-00253-z
Popis:	Abstract Background Desmoplastic changes in a tumor have been observed to affect the tumor microenvironment, leading to both the facilitation and prevention of tumor invasiveness. Methods Between 2016 and 2020, a total of 120 patients were diagnosed with gallbladder carcinoma. The cases were reviewed for the type of desmoplastic reaction, tumor grade, and stage. The type of desmoplastic reaction was classified as mature, intermediate, and immature, and they were correlated with tumor grade and stage. Results Out of the total number of cases, 21.67%, 48.33%, 25%, and 5% belonged to stages 1, 2, 3, and 4, respectively. A total of 79.2% of these cases showed desmoplastic stromal reaction, and there was a significant correlation (p
Databáze:	Directory of Open Access Journals
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