FGFR3 Alterations in the Era of Immunotherapy for Urothelial Bladder Cancer

Autor: Alec Kacew, Randy F. Sweis
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Immunology, Vol 11 (2020)
Druh dokumentu: article
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.575258
Popis: FGFR3 is a prognostic and predictive marker and is a validated therapeutic target in urothelial bladder cancer. Its utility as a marker and target in the context of immunotherapy is incompletely understood. We review the role of FGFR3 in bladder cancer and discuss preclinical and clinical clues of its effectiveness as a patient selection factor and therapeutic target in the era of immunotherapy.
Databáze: Directory of Open Access Journals