Side-Alternating Vibration Training Improves Muscle Performance in a Patient with Late-Onset Pompe Disease
| Autor: | Aneal Khan, Barbara Ramage, Ion Robu, Laura Benard |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Case Reports in Medicine, Vol 2009 (2009) |
| Druh dokumentu: | article |
| ISSN: | 1687-9627 1687-9635 |
| DOI: | 10.1155/2009/741087 |
| Popis: | Side-alternating vibration training (SAVT) was used for 15 weeks in a patient with Late-onset Pompe disease who had never used enzyme replacement or chaperone therapy. Prior to the use of SAVT, the patient had experienced declining muscle performance and her 6-minute walk distance decreased from 210 to 155 metres in 6 months. After SAVT, her 6-minute walk distance increased 70% from 166 to 282 metres, muscle jumping power increased by 64% from 83 to 166 watts, isometric knee extensor strength increased 17% from 38 to 44 Nm, and she achieved a more normal pattern of ankle, knee, and joint kinematics and kinetics. Her functional ability measured through the Rotterdam 9-item score was unchanged at 19/36. There were no elevations in serum creatine kinase or lactate. This is the first report, to our knowledge, of a performance improvement in a patient with Pompe disease using SAVT. |
| Databáze: | Directory of Open Access Journals |
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