An analysis of sleep position during young adulthood in men who develop Barrett’s Esophagus

Autor: Brian H. Nathanson, Farhad Navab
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Cogent Medicine, Vol 3, Iss 1 (2016)
Druh dokumentu: article
ISSN: 2331-205X
2331205X
DOI: 10.1080/2331205X.2016.1233684
Popis: Objective: Sleeping on the right side (right lateral decubitus position) is associated with increased acid reflux. It is unknown how sleep position during young adulthood affects patients with Barrett’s Esophagus (BE), a precursor to esophageal adenocarcinoma. Material and Methods: This retrospective study examined 58 adult men enrolled from 2001 to 2008 with a new diagnosis of BE who did not have esophageal adenocarcinoma or prior esophageal or gastric surgery. Detailed medical history included questions on sleep position during young adulthood (age 19–29). Quantile regression was used for multivariable adjustment. Results: The median age at presentation was 55 with a range of 33–91. 28 patients (48.3%) had BE lengths of at least 3 cm. Most patients (69.0%) reported sleeping on their right side only. Sleep position was associated with the age at presentation (p = 0.009). Patients who slept on their left side were the oldest at diagnosis (adjusted median age = 68.7 years) and significantly older than those sleeping on both sides or prone (age 41.2 years, p = 0.002) or their right side and either prone or supine (45.7 years, p = 0.005) or right side only (55.1 years, p = 0.03). Sleep position was not associated with BE length after multivariate adjustment (p = 0.43). Conclusion: Most patients slept on their right side during young adulthood. Patients with right side (and non-left side) sleeping were diagnosed at a younger age than left-side sleepers. This may be due to more nocturnal reflux during young adulthood.
Databáze: Directory of Open Access Journals
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