| Autor: |
Emanuele Bobbio, Entela Bollano, Christian L. Polte, Jan Ekelund, Göran Rådegran, Jakob Lundgren, Carl Haggård, Grunde Gjesdal, Oscar Braun, Sven‐Erik Bartfay, Niklas Bergh, Pia Dahlberg, Clara Hjalmarsson, Sorosh Esmaily, Ida Haugen Löfman, Aristomenis Manouras, Michael Melin, Göran Dellgren, Kristjan Karason |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
ESC Heart Failure, Vol 9, Iss 4, Pp 2654-2663 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2055-5822 |
| DOI: |
10.1002/ehf2.13990 |
| Popis: |
Abstract Aims Renal dysfunction in patients with heart failure (HF) has traditionally been attributed to declining cardiac output and renal hypoperfusion. However, other central haemodynamic aberrations may contribute to impaired kidney function. This study assessed the relationship between invasive central haemodynamic measurements from right‐heart catheterizations and measured glomerular filtration rate (mGFR) in advanced HF. Methods and results All patients referred for heart transplantation work‐up in Sweden between 1988 and 2019 were identified through the Scandiatransplant organ‐exchange organization database. Invasive haemodynamic variables and mGFR were retrieved retrospectively. A total of 1001 subjects (49 ± 13 years; 24% female) were eligible for the study. Analysis of covariance adjusted for age, sex, and centre revealed that higher right atrial pressure (RAP) displayed the strongest relationship with impaired GFR [β coefficient −0.59; 95% confidence interval (CI) –0.69 to −0.48; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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