African Swine Fever Virus F317L Protein Inhibits NF-κB Activation To Evade Host Immune Response and Promote Viral Replication

Autor: Jinping Yang, Shasha Li, Tao Feng, Xiangle Zhang, Fan Yang, Weijun Cao, Hongjun Chen, Huisheng Liu, Keshan Zhang, Zixiang Zhu, Haixue Zheng
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mSphere, Vol 6, Iss 5 (2021)
Druh dokumentu: article
ISSN: 2379-5042
DOI: 10.1128/mSphere.00658-21
Popis: African swine fever (ASF) is one of the most important pig diseases, causing a high case fatality rate and trade restrictions upon reported outbreaks. The limited understanding of the functions of the proteins of the causative agent, African swine fever virus (ASFV), has become a primary barrier to developing available commercial ASFV vaccines.
Databáze: Directory of Open Access Journals