Assessing the long-term economic impact of wheezing episodes after severe RSV disease in children from Argentina: a cost of illness analysis

Autor: Ranju Baral, Clint Pecenka, Elisabeth Vodicka, Andrea Rodríguez, Julia Dvorkin, Emiliano M Sosa, Andrea Sancilio, Karina Dueñas, Carlos Rojas-Roque, Patricia B Carruitero, Fernando P Polack, Mauricio T Caballero
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMJ Public Health, Vol 2, Iss 1 (2024)
Druh dokumentu: article
ISSN: 2753-4294
DOI: 10.1136/bmjph-2024-000975
Popis: Introduction There is lack of available data on the economic burden of wheezing episodes after severe respiratory syncytial virus (RSV) infection. This study aimed to assess the cost incurred for wheezing episodes after a severe RSV infection in children from Argentina, considering both the public health system and societal perspectives.Methods A prospective cohort was conducted from 2014 to 2022 to assess the cost of illness of wheezing episodes after severe RSV disease in children from Buenos Aires, Argentina. Direct medical and non-medical costs were estimated, along with indirect costs per episode and patient. Data pertaining to healthcare resource utilisation, indirect expenses and parental out-of-pocket costs were obtained. The overall cost per hospitalisation and health visits was calculated. Costs were quantified in US dollars using the average exchange rate on the specific date of data collection.Results A total of 256 infants experienced severe RSV disease during their first year of life and were followed over a 5-year period in Buenos Aires. Overall, 150 children between 12 and 60 months presented 429 wheezing episodes. The median number of wheezing episodes per patient was 5 (IQR 3–7). The mean cost per wheezing episode was US$191.01 (95% CI 166.37 to 215.64). The total cost per episode of wheezing was significantly higher (p
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