Analysis of sleep spindles in children with Asperger’s syndrome

Autor: Rodolfo Cebreros-Paniagua, Fructuoso Ayala-Guerrero, Erik Leonardo Mateos-Salgado, Christopher Isaac Villamar-Flores, Carlos Alberto Gutiérrez-Chávez, Ulises Jiménez-Correa
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Sleep Science, Vol 14, Iss 3, Pp 201-206 (2021)
Druh dokumentu: article
ISSN: 1984-0659
1984-0063
DOI: 10.5935/1984-0063.20200059
Popis: Sleep spindles are an element of the sleep microstructure observed on the EEG during the NREM sleep phase. Sleep spindles are associated to sleep stability functions as well as memory consolidation and optimization of different cognitive processes. On the other hand, Asperger’s syndrome (AS) is a generalized developmental disorder in which cognitive and sleep disturbances have been described. In this study we analyzed different characteristics of sleep spindles in a group of children with AS and compared them with sleep spindles of a group of children with typical development paired by age; both groups ranged from 6 to 12 years of age and were all male. We observed a statistically significant decrease in sleep spindles intrinsic frequency in different brain regions in the AS group in relation to the typical development group. This finding could be due to immaturity in brain regions related to the integration of sleep spindles; and this immaturity could be related with cognitive aspects in these patients.
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