Clinical and programmatic outcomes of HIV-exposed infants enrolled in care at geographically diverse clinics, 1997-2021: A cohort study.

Autor: Andrew Edmonds, Ellen Brazier, Beverly S Musick, Marcel Yotebieng, John Humphrey, Lisa L Abuogi, Adebola Adedimeji, Olivia Keiser, Malango Msukwa, James G Carlucci, Marcelle Maia, Jorge A Pinto, Valériane Leroy, Mary-Ann Davies, Kara K Wools-Kaloustian, IeDEA
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: PLoS Medicine, Vol 19, Iss 9, p e1004089 (2022)
Druh dokumentu: article
ISSN: 1549-1277
1549-1676
DOI: 10.1371/journal.pmed.1004089
Popis: BackgroundAlthough 1·3 million women with HIV give birth annually, care and outcomes for HIV-exposed infants remain incompletely understood. We analyzed programmatic and health indicators in a large, multidecade global dataset of linked mother-infant records from clinics and programs associated with the International epidemiology Databases to Evaluate AIDS (IeDEA) consortium.Methods and findingsHIV-exposed infants were eligible for this retrospective cohort analysis if enrolled at ConclusionsWhile there was marked regional and temporal heterogeneity in clinical and programmatic outcomes, infant LTFU was high across all regions and time periods. Further efforts are needed to keep HIV-exposed infants in care to receive essential services to reduce HIV infection and mortality.
Databáze: Directory of Open Access Journals
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