The Rising Importance of Proton Magnetic Resonance Spectroscopy in the Diagnosis of Selected Neurodegenerative Diseases of the Brain

Autor: Katarzyna Szmyt, Maciej Superson, Klaudia Wilk-Trytko, Katarzyna Szymańska, Kamil Walczak, Sylwia Samojedny, Wiktoria Mika, Julia Krasnoborska, Julia Zarębska
Jazyk: English<br />Spanish; Castilian<br />Polish<br />Russian<br />Ukrainian
Rok vydání: 2024
Předmět:
Zdroj: Journal of Education, Health and Sport, Vol 72 (2024)
Druh dokumentu: article
ISSN: 2391-8306
DOI: 10.12775/JEHS.2024.72.51253
Popis: Introduction: Neurodegenerative diseases pose a significant diagnostic challenge due to the increasing elderly population and the rising prevalence of these conditions. State of Knowledge: Differential diagnosis among these diseases is particularly challenging; thus, numerous clinical trials have been conducted to identify markers that could facilitate accurate disease diagnosis. Among various diagnostic approaches, imaging techniques play a crucial role, especially magnetic resonance imaging (MRI), which includes advanced modalities such as proton magnetic resonance spectroscopy (¹H-MRS). ¹H-MRS offers a non-invasive assessment of neurometabolite profiles, providing critical information that aids in precise diagnosis. Conclusions: With ongoing clinical trials, the importance of ¹H-MRS in diagnosing neurodegenerative diseases continues to grow. This paper reviews the results of recent and relevant clinical trials examining changes in ¹H-MRS in the most prevalent neurodegenerative diseases.
Databáze: Directory of Open Access Journals