Mitigating Benzodiazepine Dependence and the Risk of Drug-Induced QTc Prolongation in the Treatment of Gastroparesis: A Case Report

Autor:	Karley Tranchina, Derek Matlock, Carlos Hernandez, Jacques Turgeon, Jennifer M. Bingham
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	benzodiazepine dependence QTc prolongation pharmacist medication safety gastroparesis Medicine (General) R5-920
Zdroj:	Medicina, Vol 58, Iss 3, p 409 (2022)
Druh dokumentu:	article
ISSN:	58030409 1648-9144 1010-660X
DOI:	10.3390/medicina58030409
Popis:	Patients are often faced with challenges when it comes to safe therapeutic options. An 89-year-old female with a history of arrhythmias and refractory gastroparesis complained of adverse drug events from her benzodiazepine. While performing a comprehensive medication review and a medication safety review using an advanced clinical decision support system, the pharmacist successfully tapered off the benzodiazepine to a safer alternative antidepressant indicated for the treatment of gastroparesis. Special attention was given to selecting drugs with less QT prolongation risk, based on her age, current drug regimen, previous medical history, and presence of polypharmacy.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/4a4013664d38464096636472c4d45aa4 Zobrazit plný text záznamu View record in DOAJ